Pinto,

I put two 220 grain Core-Lokts out of my Husqvarna Aught Six through a Cow moose broadside at seventy yards. Both shots were behind the shoulder and both exited leaving great wound channels. I got better penetration from them than I did with the 350 grain Interlock in the .450 Marlin that I shot a Bull Moose with. That bullet did not exit and came apart. Still brought things to a speedy conclusion though.