I have 2 aftermarket one in eights, never had an issue with 40 VMs or BKs doing anything untoward. You'd have to really make them scream, which seems to me counterproductive anyway in a "big" 22 bigger than BR.
My old factory 1 in 9 Savage also shot 40s without issue, they never blew up, but the harder I pushed, the less well they shot.
I'm just WAITING for someone to neck down those x47 Lapua cases into some kind of nutz 22 wildcatt. Watched a friend shoot his 6x47 bench rifles and was impressed.


Up hills slow,
Down hills fast
Tonnage first and
Safety last.