With the 105 amax, I'm comfortable to 750-ish. (Edit: but thats only because I haven't run that bullet farther than that yet on steel, in that chambering.)
Shot a big muley at 484 last fall, first one was hard quartering in front of the onside hind, and it rolled him hard at the hit. He did manage to get back to his feet, and since the shooting is the fun part I put a second one broadside through both shoulders just for giggles.
That one smashed him off his feet as well.
Nope.
