I'll disagree that Dillons are only for handguns and 650's for single calibers.
If your brass is prepped and die plates good, runout is well within tolerances for anything not benchrest. Just the other day I got two of my best groups ever, both under .250 for five at 100. The worst groups were all under a half inch, this with guns I probably have 800 bucks (counting their second barrels) into.
Changeovers on the 650 only take about five minutes, and that's a good time to also wipe everything clean for the run. I've got color coded Allen wrenches and bolts, which saves a few seconds, too. And if you plan your reloads, sometimes all you have to do is change the head and start banging away.
Progressives (um, excuse me, SEQUENTIALS) rule.
