I worked with it some years ago. It's an interesting round, but not easy to handload. In particular, it's hard to keep the bullets from setting back in feeding, because the base is below the neck, hanging in space.
If you're buying or building a pistol from scratch, go with a 10mm. If you already have a .45 ACP, it adds some interesting flexibility, with only a barrel and dies.
The 40 Super is a better way to go IMHO.
