Much is often made of a SS as being a purist's gun, who plans to make only one shot at game. But there are practical advantages, too. I will contend the #1 (or any other single shot) gives you the best chance at the best first shot out of a rifle.
1. shorter OAL for a given barrel length - or keep the OAL and have a longer barrel
2. Bullets can be any desired shape, without worrying about feeding out of a magazine, or setting off a chain fire in a tubular magazine
3. Bullet seating has more flexibility - no need to stay within mag lengths
4. Action strength can be an advantage, within safe load limits, of course.
The intangible issues of course, would be finding moderately priced rifles with spectacular wood, tuning for better accuracy, which brings its own satisfaction, and yes, collecting interesting variations.
