I just put fiber optic sights on my old TC New Englander, 1-48 twist. I had sighted in with pyrodex select and home cast 250 gr. REAL bullets, but picked up some 777 to try. With the same measure setting(80 gr.), the 777 was hitting 6 inches high and 3 inches right at 50 yards. Seems to be more speed on this one. I didn't get the chance to shoot for groups before running out of time and bullets, but it seemed to be pretty accurate as I was walking it into the bull.
Cleanup seemed to be easier for me, but one range session doesn't tell the whole story.
I've always had trouble getting pyrodex cleaned up in this rifle. After pumping hot soapy water through it and a rinse, I'd run patches with TC #13 that were still loaded with a dark brown residue. Sometimes it took a couple cleanings during the following week to get it clean. Don't know if it's the high humidity causing excessive fouling or what. I've always used bore butter for a lube since they advertise it as reducing fouling.