I've ran the 25-06, 6-06, 6.5-06, 270, and 30-06 quite a bit. With today's bullet inventory I could put all the choices in a bucket, pick blindly, and do the same things with any of them. Your 25-06 thinking will be perfectly suitable. I'd pick it over 6-06 or 6.5-06 having owned all 3. I always end up comparing both of the others to the 25-06 anyway.
If we need to get all into the gack: Run the calcs on .243-105s at 3150, .257-115s at 3200, and .264 130s at 3050 on the 3 mentioned cases and you'll see they are a little more similar than many think.
