I could have sworn that Mule Deer said that R-22 was more sensitive to temp swings than the Hodgdon Extreme powders.
He did.
And he's run some controlled tests to draw that conclusion.
Nonetheless, I've run it in several chamberings & have had no problems with loads developed in 50-60 degrees down to around 10 degrees or so.
But then again, I've not run any controlled tests.
MM