42 grs. of IMR 4320 with a Nosler solid base 150 was my go to deer round. 2575 FPS out of an 99F. ---Then Nosler stopped making the solid base and I went to Hornady 150SST bullets and Reloader #12 with 44.4 grains ,fed 210 primer, Rem brass and 2700 FPS and 1/2" 3 shot groups at @100. I still have a couple pounds of discontinued Reloader 12.
