I have several friends who carry Colt Defender .45s and all of them carry CorBon PowR'Ball. From a 3" barrel is unlikely there is going to be any expansion in a real body vs. Jello for any ammo.
http://www.corbon.com/corboncart/glaser/pow-rball/pb45165-20I carry PB in my .38 Super...100 grain bullet at 1525 chronographed...
Bob