Wife has a Smith Model 60, I have an SP101. What that really means is she has 2 guns that handle the same, take the same speedloaders, and she grabs whichever one she's closest to.
No matter what else I have on me, she can get to something she's used to. Both are fired more with wax loads than real ammo. It's the only kind of practice she can do, regularly. Tried to get her going with several autoloaders; she never could operate them consistently. The Ruger took action work, even for my use. Now it's as easy and slick as the Smith, almost.