bglimpse,

I hunt everything with my 338wm, this would include deer, coyote, elk, moose, grizzly, black bear, wolf, and anything else on my tag list. My load of choice is 250grn Swift AFrames, on top of 71 grains of H4831sc. I generally eat up to the hole with this load.

Dead is dead, I would just use what shoots well in your rifle.