Can you push them fast enough to get good initial expansion on light game like deer will be the question. With a .358, in a M700 at least, case capacity as relates to COAL, and also sometimes bullet ogive receding into the case neck, are the bugaboos… so with a 250 at 2.82” COAL velocity is going to be capped at a max that may or may not be enough to give optimum results from a given bullet. I decided even a 225 NP @ 2500 fps was a bit “polite” for my tastes on deer, though it’d be good for elk, I would think.
…. however in reality I suspect ANY .35 cal rifle hunting bullet from a .358 is gonna be very effective.
The most devastating wound channel I’ve ever personally seen was from a factory 200-grain Silvertip on a doe at about 150 yards from a .358 BLR I had for a minute. WOW. Note to self: avoid getting shot by a 200-gn Silvertip.