I spent several seasons with my first 280AI and 63gr of N165 and 140 Accubonds. Never had a whitetail run more than 75 yards however got tiny entrance and exit holes. Most were heart/lung placement. Most deer ran. Big internal destruction but almost no blood trails. The exception to this was a 275 yard shot doe. Much greater blood loss and exit hole. I have never fully understood the internal ballistics of the Nosler Accubond. Given that it is a bonded bullet, could I have still been getting core separation at high speed? Probably going close to 3000 fps at under 100 y ranges.