Thanks to all that replied. I am having internet problems here in Australia.
Currently, I have tried RE22, RE25, H1000, H4350 and RE15, RE15 was no good without filler being used.
I have Retumbo on hand, so I will give that a try next. My rifle is a CZ 550 custom shop rifle with a mercury recoil reducer, recoil is stiffer than my 500 Nitro double, but that rifle is a few pounds heavier and only pushes 570gr pills to close on 2200fps.
I have pushed 600gr PP's above 2350fps in the 505, but a visit to the dentist may be in order if I shoot 15-20 of those off in a session!
Thanks again Gunner500.

Cheers.