I have only shot two elk and one bear with the Nosler 260 ptn but it did the job very well. Full penetration and good expansion, with good accuracy. I took one moose with a Federal factory 300 gr RN. It was by coincidence the farthest I have shot a moose, just over 300 yards. Full penetration and adequate expansion. That's it for my game experience. The Hornady 270's shoot accurately from my Ruger RSM too.