I do prefer hunting with iron sights. My eyes are still good enough to allow me to do this.
I have shot a couple of buffalo and elephant at 10 yards or under with irons but never with a scope so it would be hard to compare.
The most important thing is to have a rifle that fits whether it is for irons or a scope so that when you shoulder it you can shoot.
BTW at less than 10 feet it does not matter, both of my eyes are closed, I do not want to see what will happen next.
