It was Fred Barker, in an article in Preciion Shooter maybe a decade ago, that started me trying Mag Pro, RL25 in the 270. Fred also used MRP II and some other newer slower powders in a 25" PacNor barrel on a a Mauser action.
He said we were missing the boat with the 270 by not trying powders slower than H4831. I think in terms of velocity with the stuff 140 and heavier he was right.
And guys using theses 165-170 gr VLD bullets will find that out shortly I think.