Put a 6x45, aka 6mm-223, Shaw barrel on what was a .223 Savage Axis rifle late last year. Gent I shoot with at range gave me a set of Hornady dies for the 6x45 cartridge.

I do enjoy shooting my 6x45. Very happy with its accuracy. As mentioned, Ramshot TAC does well in the cartridge, but if you ask Western/Accurate/Ramshot for TAC 6x45 load data....you'll be told TAC is too slow for the 6X45 and use what they list. Least ways, what happened to me. IMR8208 has done well for me too. But then, many of the powders recommended for the .223 cartridge should perform well in the 6x45 with the correct charge.

What bullet for hunting? Sorry, I just shoot paper. But do know the Nosler 70 gr Varmegeddon 6mm bullet shoots well for me when it comes to accuracy. But then, I've tried a variety of bullets, up to 105 grain, with decent accuracy that would be good enough for hunting.