If you're looking for variety but also practicalness, elk's suggestion above is spot on.
Lots of folks are surprised at the .375 H&H's relative lack of recoil, effectiveness on smaller game without excessive damage, and availability of rounds. I've settled on the 260 Partition in mine, and while not exactly a long range setup, it has proven ridiculously effective on black bear, elk, whitetail, wolf and antelope. Never shot a moose with it, but would not be concerned about it's ability to.
