Not a gunwriter, but, will offer my opinion. I have varmint rifles, deer rifles and a "medium bore" just in case a cape buffalo escapes from the local zoo. I have one "all-purpose" rifle that will be the last to go in the event of zombie apocalypse or democrat election victory. I could happily hunt, defend the homestead and plink with my faux-NULA CLR in 30-06 for the rest of my days. With JB's 165gr Partition load, I wouldn't feel undergunned on anything but the big 5, and the smaller stuff can't be too dead.