Good evening. I am sure you will get a ton of responses but it boils down to how much you want to spend. For Cape buffalo, THE scope in my view is the Leupold 1.75X6X32 (E) with a heavy duplex. Buffalo at 25 yards and a kudu at a lasered 352. j
I used one of these on my .375 H&H last trip and ended up leaving it with my PH who had been coveting it. Never wished for anything else.
