There's an ass for every seat.
The .30-06 is as near a "perfect" cartridge as we will ever get. 110 years of popularity lends credence to that statement.
Pick a bullet, work up an accurate load, and go use it. With bullet technology being what it is today, the old distinctions of bullet weight determining end use are blurred. A generation ago, 130's weren't good for much else than varmint shooting. Now, a 130 grain TTSX makes for a dandy big game bullet for example.