The 350's will put a big hole in and out. Years ago a friend had has gong set up at the 50 yd line, 1" thick steel plate. I was shooting 350 gr speers at ~2500 fps out of my Lott. Darn near punched a hole through the plate.
For those who can shoot a Lott from any field position with 500's and ignore recoil, more power to you. I could never ignore the recoil from the 500's. The 350's on the other hand you could shoot from any position and ignore the recoil. I'd also expect better terminal performance on game from the 350's due to the higher impact velocity.
