The 'sensitivity' of powder can be some what negated by loading small batches of ammo, enough for a specific hunt. Consider the temperature range of the hunt and the most likely time of day that will produce a kill as temperature can vary through out the day.
For me I load hunting ammo that is most effective in the 32-45 degree range which is essentially 40 degrees. Most kills come in the first 2 hours of daylight and the last hour of daylight.
For targets consider historical temperatures for the time day and location of a match.
