I load my 375 H&H up with 260 gr. partitions. These are the second's from SPS, but they shoot damn well in my rifle...
This^ (or even the 300). Either will expand just fine, even on deer, and neither will explode in a 'worst-case-scenario' if you should happen to hit one of the big bones in a moose shoulder. The Interlocks can work well, and I have seen "eat-up-to-the-hole" instances with them on caribou. But I have also seen them get pretty shredded and fail to fully penetrate when used on seals (which would have been less that 200 pounds.)
