I used a 365gr beartooth from an 18" 45lc rifle to kill a whitetail deer, about your velocity. I hit it square on at 80 yds and it traveled the full length of the deer and lodged under the hide on the hind. A solid 30" trip through the same stuff you'll see. I'd have no fear. Don't expect gushing blood trails, but very dead elk.

Originally Posted by BrentD

I would not buy something that runs on any kind of primer given the possibility of primer shortages and even regulations. In fact, why not buy a flintlock? Really. Rocks aren't going away anytime soon.