Experience of only 1 smallish bull taken at 125 yards, short answer, it should pass through from side to side. As stated above, don't expect a massive blood trail.
The one I shot was with a 300 gr cnc bullet pushed by a load of H110.
Shot was a slight angle towards me. Bullet entered just on the front edge of the shoulder and exited behind the off shoulder.
The bull traveled about another 100 yards and laid down. I waited about 5 minutes until he expired.
I equated it to the 3 elk taken with a muzzleloader at similar ranges. One with a lead maxi-ball punched right through both shoulders of a cow at 75 yards.