I have QR extension rings on my Winchester 70 in 375 H&H, otherwise the only Leupold Vari-X IIc 2-7x28 tube would be too short to reach proper eye relief.

If I was going back to Africa, I would bring my Interarms Mark X mannlichers in 7x57 and 9.3x62 with Leopold QRs and an extra scope pre-zeroed for each rifle, probably 2-7x33s or 2.5-8x36s, all with HD reticles.

In the U.S., I always carry a spare rifle, but that isn't practical, so a rifle set up with QR mounts and a spare, pre-zeroed, scope is a good alternative.