Nice score on the 375! Have owned several Vanguards and been happy with them all. I'd put a low power variable Leupold VX3 on it and forget about it. I don't find a 375 to kick as sharply as say a 338 Win mag. My two 375's both wear 6X Leupolds, but probably wouldn't be the best for close in cover shots. Especially in bear country!
