Not the 375 H&H, but I elk hunt with a 375 Ruger Guide Gun with the 20" barrel. I load a Nosler 300gr. Accubond and I get a chronographed 2590fps. Far as scope I use a Leupold VX3 2.5-8x36mm with Alaskan Arms quick detach rings sighted in at 200yds. Then I have NECG Ruger Ghost Ring Peep sight for thick timber areas.
