It's very effective against ticks, if you can tolerate extremely tight fitting clothing.
I had a set that I couldn't wear because it was so tight fitting that it made me very uncomfortable.....especially in warm weather.
I gave the outfit to my hunting buddy (who had already had a case of Lyme desease and didn't want another) and he's been wearing for a couple of hunting seasons now and has not had an issue with ticks.
The name Rhino Skin is very appropriate though, because it truly is skin tight.