If shot well. I made some good dollars going into the bush to kill wounded bear a couple decades ago. Their fat sealls the wound chanel and you don't usually get much blood trail to follow. A wounded angry bear needs a central nervous system hit to put down with authority. If you keep your nerve, that is the ideal shot when calling, as they are coming in for dinner and typically come in hot, and face on. Spinal shots I have taken a number with 6.5x55. I moved up to 45/70 single shot and finally to 338 win mag. I only got two with that, and quit helping out the outfitters in the mid 1990's as a slow economy had them balk at my price. I plan on using a 257 bob this next fall and it is hardly more powerful than the 250-3000.
Randy
