IMR4350 will push bullets accurately to their destination from weights of 150 through 190 grains. All that I have tried worked well. I used 60.5 gr I4350 with a 150 gr Nosler solid base. 57-58.5 gr of I4350 with a Hornady BTSP 165 gr, and 55 gr of I4350 and a 180 gr Hornady BTSP. The 190 will use the same powder charge as the 180. It's a great powder for the '06 -- almost as ood as H4831, H414, RL19. Hope you get the glitches worked out. All my '06's shoot real well and load development has been easy.