I currently load the 110 grain Barnes TTSX in my 270 WSM and really like it. I am in California and had to find a no-lead load for my 270 WSM. I tried the 130 grain Barnes TSX but the accuracy was just not what I wanted. On a lark I tried the 110 grain TTSX and the accuracy was great and the speed impressive.

You should work up to this load from a few grains below, but I shoot the following:

Winchester cases
Fed 215M primers
67 grains IMR 4350
110 grain Barnes Tipped TSX
velocity = 3600 fps
groups = very good, with the best so far 0.323" at 100 yards

So far I have only shot a few coyotes and one antelope with this load. Great performance in every case, you can sure hear that bullet hit, very noticable "whop" when they strike.