Was hunting bull elk in AZ a few years back. I used a 300 win mag loaded with 200 grain NP's zero'd for 300 yards.

Spotted a bull on a hillside that I knew was aways over there.
Got a good rest turned my scope to 12 x and
set the horizontal hair on the bulls back and touched off, bullet
hit 3 feet below of where he was standing. I then set the top
point of the bottom plex on the bulls back and touched off.
It dropped him and it dropped the small cow behind him, the one I couldnt see. One shot, one bullet, two dead elk, complete penetration on both animals.