I've shot a lot of deer and elk with my old 25-06 using 120g partitions at 2950fps. But a few years ago I bought a 270WSM and shoot 140g TSX at 3350fps.

My 25-06 has been used only as a varmit gun ever since. The 25 is more plesant to shot 40-50 rounds at Jack rabbits. Where as the 1 or 2 shots I take at big is no big deal out of the 270WSM.