I've used .22 short HP's from a 6" SA revolver for 30-some years.
Shoot critters broadside thru the ear on a line to exit the other ear. Instant dispatch, usually no exit and if it does exit.......there's already a hole there.
Only exception is skunks. I slip a .22 LR into the revolver and pop them broadside behind the shoulder. Not fool-proof......but reduces sprayers significantly.
