Just found this thread so sorry to bring up old wounds. Anyways, I think I have found another cartridge that RL-17 seems works very well in. It's a 338-06AI. Now I'm not claiming to get 150-200 fps gains over other "established" powders but there are definitely gains to be had. 65-90 fps with great accuracy is what I experinced using 210 and 225 gr bullets. If the accuracy hadn't come along with this gain in velocity I would not be writing this. Now, if a person checks a ballistic table, gains like these for most real world hunting situations make very little difference but when you can sneak that much more out of your cartridge and still have outstanding accuracy, who wouldn't take it and run. Cheers.