I'm not to sure I would deviate from 4320, especially pushing 25gr. pills. I will admit to using a lot of 8208 behind 25gr. bullets. I got real lucky and have a load with 4320 and one with 8208 that shoot to the same point of impact. That 8208 burns pretty clean too.
Big Game with 30gr. I've heard is a real winner and rates real high when using it in the 17-204, but me, I still use H414/W760 behind 30's. Guess I'm old fashion. blush