I successfully used that bullet on a BC grizzly and black bear hunt a few years ago. This from my 338-06. The blackie was a bang flop and the grizz did about ten 360's biting at the exit wound then expired. The combo you suggest is more than plenty for what you plan to hunt. Last June kudu, wildebeast and gembuck dropped to a 7x57 and a 358 Win without much fanfare.
