Must admit that I have never used H100v in a 300WM, IMO it is a bit fast burning unless you are shooting 150's. I shot 165's with H4831 for years with Fed 210's.
With 180's my powder of choice has always been RL22 with Fed215's.
In my current 300WM my favorite load is 210VLD's with H1000 and Fed 215's

Give us a bit more info on the bullet,primer, powder combo