Keep velocity under 3000 fps with cup and core bullets, and you're a step in the right dirrection. When I was shooting a 300wm as my main hunting rifle, I settled on 180grn Hornady Interlocks at 2950 +/-, and that seemed to solve a lot of the mess. The 150grn and bullets of frangible design will tear a carcass up. Shoot a sturdy bullet in the ribs and you'll have no more damage than any other standard deer rifle.
That said, my 257 Roberts with 115 ballistic tips at 2800 fps has done everything I've needed for a deer rifle, and doesn't make a mess on the receiving end.
