I got a .224 TTH before last hunting season, but due to a knee injury didn't get to use it on big game last fall. But based on experience with the .22-250 and .220 Swift, I'm guessing the 40-grain Cutting Edge Raptor at 4400 fps and the 60-grain Nosler Partition at 3700 will do the job well.

“Montana seems to me to be what a small boy would think Texas is like from hearing Texans.”
John Steinbeck