I have used Sierra 120 ProHunter bullets with 47 gr of H4350. This is lighter bullet but my experiences with 3 medium size deer last year left something lacking. I hunt on edge of farm and neighbors do not permit anyone on their land. Deer I kill need to drop quickly with out long distance travel. The deer hit with Sierra ProHunter bullets were killed with one shot but traveled twice as far as deer shot with the other bullets I have used. One large Tennessee buck traveled 200 yards hit it the lungs and no blood trail.
I past I have used Hornady 139 soft point interlock bullets over 47 gr over H4350 and 46gr H380. All one shot kills with very satisfactory bullet performance.
All shots on deer have been under 200 yards.
This year I am loading Hornady 162sst bullets with 45 gr of imr4350 for my hunts. My rifle really likes this bullet. I am wanting clean kills with good blood trail and short runs from deer after being hit.