I used a 270 loaded with whatever 150 grain was on sale for over 20 years on moose out to 300 yards and never lost one.
I can't remember any that took more than one shot except to finish off the lung shot ones fast.
I'm not talking a few moose but one every year with a bunch of mulies and the odd black bear thrown in.
As long as you don't gut shoot the animal it will drop with a 150.
270 with 150's is a perfect match and doesn't waste meat if you do your part.
