The dodge trucks aren't bad, the only issue you can expect is somewhere around 100k on the odo you'll need to replace the ball ends on the front end, and perhaps the front hubs (one way bearings) if it's 4X4.
Probably dependent on the roads travelled. My 2003 went 245k on the balljoints and had the original wheel hubs when I sold it at 297k miles. I also had stock wheels and tires on it and kept them balanced.
