I've probably killed 100 whitetails with Federal 80 grain factory loads from a variety of 243s and 6MMs, much of it old red box ammo that we bought at a store closing for $4 or $5 per box of 20. They work fine when you can pick your shots and shot 'em broadside, where you don't need to get much penetration to get into the vitals.

I prefer shooting my deer with Partitions when using .224", .243", and .257" bore rifles, particularly if taking a wall-hanger might hinge on taking a shot that would require several inches of penetration.