Ive got molds for that NEI 350 grain,and several various brands of molds for 405 grain, 450 grain,535 grain .458 molds and Ive tried them all,in my 458 win, 458 lott and 450 marlin in addition to my browning single shot falling block, but at some point I think a reasonable route to take is to ask yourself,

"is this cast bullet,accurate enough and will it do its intended job well under almost any likely condition, at any reasonable range on the game I hunt?"
the 350 and 405 grain bullets are the only ones short enough to function and still provide higher velocity's in my 450 marlin BLR and the marlin 45/70 lever action I recently sold to buy the BLR, and yes even the cast gas check 350 grain has amazing penetration, on elk and deer in fact Ive yet to recover one, nor has anyone else I remember using one, and I load for many of the guys I hunt with.